Ngwaahịa
Ihe nrịbama obi - Troponin I
Troponin bụ protein na-achịkwa eriri akwara na sel anụ ahụ, nke na-achịkwa nkenke mbanye n'etiti filament muscle siri ike na nke dị gịrịgịrị n'oge myocardial myocardial.Ọ mejupụtara subunits atọ: troponin T (TNT), troponin I (TNI) na troponin C (TNC).Okwu nke subtypes atọ dị na akwara skeletal na myocardium na-achịkwakwa mkpụrụ ndụ ihe nketa dị iche iche.Ọdịnaya nke troponin obi na ọbara nkịtị dị ala karịa nke enzymes myocardial ndị ọzọ, mana itinye uche na cardiomyocytes dị oke elu.Mgbe akpụkpọ ahụ myocardial cell na-adịghị, cTnI enweghị ike ịbanye n'ime akpụkpọ ahụ cell n'ime mgbasa ọbara.Mgbe mkpụrụ ndụ myocardial na-emebi mmebi na necrosis n'ihi ischemia na hypoxia, a na-ahapụ cTnI n'ime ọbara site na mpempe cell mebiri emebi.Ntinye uche nke cTnI na-amalite ịrị elu 3-4 awa mgbe ihe omume AMI gasịrị, na-arị elu na awa 12-24, ma na-aga n'ihu maka ụbọchị 5-10.Ya mere, mkpebi siri ike nke cTnI n'ime ọbara abụrụla ihe ngosi dị mma maka nleba anya nke ịdị irè nke reperfusion na reperfusion na ndị ọrịa AMI.cTnI abụghị naanị nwere nkọwa siri ike, kamakwa ọ nwere mmetụta dị elu na ogologo oge.Ya mere, enwere ike iji cTnI dị ka ihe nrịbama dị mkpa iji nyere aka n'ịchọpụta mmerụ ahụ nke myocardial, karịsịa nnukwu myocardial infarction.
Isi akụrụngwa
| Microparticles (M): | 0.13mg/ml Microparticles tinyere mgbochi troponin I ultra antibody |
| Reagent 1 (R1): | Ihe nchekwa 0.1M Tris |
| Reagent 2 (R2): | 0.5μg/ml Alkaline phosphatase akpọrọ antitroponin I ultra |
| Ngwọta nhicha: | 0.05% surfactant, 0.9% ihe nchekwa sodium chloride |
| Substrate: | AMPPD na nchekwa AMP |
| Calibrator (nhọrọ): | Troponin I ultra antigen |
| Ihe njikwa (nhọrọ): | Troponin I ultra antigen |
Mara:
1.Components na-adịghị agbanwe agbanwe n'etiti ogbe nke reagent ibe;
2.Lee akara karama calibrator maka itinye uche calibrator;
3.Lee akara akara karama akara maka ntinye uche nke njikwa.
Nchekwa na Nkwenye
1. Nchekwa: 2℃～8℃, zere ìhè anyanwụ kpọmkwem.
2.Validity: ngwaahịa anaghị emeghe dị irè maka ọnwa 12 n'okpuru ọnọdụ akọwapụtara.
3.Calibrators na njikwa mgbe dissolving nwere ike ịchekwa ụbọchị 14 na 2℃～8 ℃ gbara ọchịchịrị gburugburu.
Ngwa ngwa
Sistemụ CLIA akpaghị aka nke Illumaxbio (lumiflx16,lumiflx16s, lumilite8, lumilite8s).
